Research Projects - Center for the Prevention and Treatment of Visual Loss
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Center for the Prevention and Treatment of Visual Loss

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Research Projects

VA Funded

VA Center for the Prevention and Treatment of Visual Loss
Randy Kardon, MD, Director
July 2009 - June 2019

Therapy of Nocturnal Intraocular Pressure Elevation Causing Glaucoma Progression
Michael Anderson, PhD, Co-Principal Investigator and Markus Kuehn, PhD, Co-Principal Investigator
January 2015 - December 2018

Mechanisms of neuronal dysfunction in mild Traumatic Brain Injury
Laura Dutca, PhD, Principal Investigator
August 2016 - July 2021

Automated Assessment of Optic Nerve Edema with Low-Cost Imaging
Mona Garvin, PhD, Principal Investigator
April 2016 - March 2020

CaMKII as a regulator of diabetic retinopathy
Isabella Grumbach, MD, PhD, Principal Investigator
January 2015 - December 2016

Chronic Effects of Blast Injury: Analyses of Alzheimer Related Pathology
Matthew Harper, PhD, Co-Principal Investigator
January 2014 - December 2018

CENC-Visual Sensory Impairments and Progession Following Mild Traumatic Bain Injury
Randy Kardon, MD, PhD, Principal Investigator
January 2016 - December 2018

New! Bioassay to Predict the Development and Progression of Glaucoma
Markus Kuehn, PhD, Principal Investigator
July 2018 - June 2022

Stem Cell Therapy for Glaucoma
Markus Kuehn, PhD, Principal Investigator
July 2014 - March 2018

 Photosensitivity as a preclinical assessment for treatment of post-traumatic headache
Andrew Russo, PhD, Co-Principal Investigator and Andrew Pieper, MD, PhD, Co-Principal Investigator
February 2016 - January 2020

Identification and treatment of brain regions causing post-traumatic headache
Levi Sowers, PhD, Principal Investigator
January 2016 - December 2020

Diabetic Neuropathy: Function-Structure of corneal nerves to assess injury-repair
Mark Yorek, PhD, Principal Investigator
January 2013 - December 2016

Testing the Peripheral Visual Field- Obtaining the Full View
Michael Wall, MD, Principal Investigator
October 2015 - September 2019

Calmodulin kinase II inhibition as novel molecular treatment of hypertension
Isabella Grumbach, MD, PhD, Principal Investigator
July 2013 - June 2017

Federal, Non-VA Funded

Three Dimensional Structure-Function Relationships in Glaucoma from SD-OCT
Michael Abramoff, MD, PhD, Principal Investigator
April 2008 - November 2016

Genetic Dissection of Pigmentary Glaucoma
Michael Anderson, PhD, Principal Investigator
February 2014 - January 2018

Molecular Genetics of Normal Tension Glaucoma
Michael Anderson, PhD, Principal Investigator
April 2014 - March 2018

3D Image Analysis approach to determine severity and cause of optic nerve edema
Mona Garvin, PhD, Principal Investigator
May 2013 - April 2018

Prevention and Treatment of TBI-Mediated visual and Brain Damage Using a Novel Protective Compound
Matthew Harper, PhD, Co-Principal Investigator
October 2014 - October 2017

Use of Photo-Electromyogram to Objectively Diagnose and Monitor Treatment of Post-TBI Light Sensitivity
Randy Kardon, MD, PhD, Principal Investigator
September 2011 - September 2016

New! Effect of exogenous fatty acids on diabetes neural/neurovascular complications
Mark Yorek, PhD, Principal Investigator
December 2015 - November 2019

CaMKII regulates key mechanisms of vascular response to injury in vivo
Isabella Grumbach, MD, PhD, Principal Investigator
April 2012 - March 2017

Foundation Funded

Audrey and LaVern Busse Neuro-Ophthalmology Research Fund
Randy Kardon, MD, PhD, Principal Investigator
2015 - 2016

Eye Fixation Stability for Evaluating Alzheimer Disease using OCT-based Quantification of Retinal Movements
Randy Kardon, MD, PhD, Principal Investigator
2015 - 2016

Commerically Funded

New! Effect of LCZ696 on Diabetic Vascular and Neural Complications
Mark Yorek, PhD, Principal Investigator
November 2015 - November 2017

Training Programs

 

Previously Funded

Cholinergic Drugs for Reversal of Visual Deficits in Glaucoma
Randy Kardon, MD, PhD, Principal Investigator
October 2010 - September 2014

Early Detection of Glaucoma Using Raman Spectroscopy
Matthew Harper, PhD, Principal Investigator
January 2012 - December 2013

Prevention of Hemorrhage and Death after Traumatic Blast Injury (TBI)
Randy Kardon, MD, PhD, Principal Investigator
October 2010 - September 2014

Improved Assessment of Visual Field Change
Michael Wall, MD, Principal Investigator
July 2010 - June 2014

Characterization of a Novel Model of Traumatic Brain Injury
Matthew Harper, PhD, Principal Investigator
October 2010 - September 2013

Computer Aided Detection of Diabetic Retinopathy in Veterans with Disabilities
Michael Abramoff, MD, PhD, Principal Investigator
January 2011 - December 2013

Genetics of Quantitative Traits Associated with Glaucoma
Michael Anderson, PhD, Co-Investigator
July 2009 - June 2014

Prevention of Diabetic Neuropathy with ACE Inhibitors
Mark Yorek, PhD, Princpal Investigator
September 2008 - May 2014

Diagnosis and Treatment Assessment of Diabetic Peripheral Neuropathy in Humans by Relating Confocal Microscopy of Corneal Nerves to Corneal Sensation
Randy Kardon, MD, PhD, Principal Investigator
2012-2013

Anti-CGRP Therapeutics
Andrew Russo, PhD, Principal Investigator
January 2011 - June 2013

Cyropreservation of mouse lines
Michael Anderson, PhD, Principal Investigator
2012 - 2014

Improved Assessment of Visual Field Change
Michael Wall, MD, Principal Investigator
July 2010 - December 2014

Retinal Vessel Measurements as Clinically Useful Predictors in Veterans
Michael Abramoff, MD, PhD, Principal Investigator
April 2013 - March 2015

Glaucoma Assessment Using a Mulitmodality Image Analysis Approach
Mona Garvin, PhD, Principal Investigator
April 2012 - March 2015

Insulin Resistance and Vascular Complications in Obesity and Type 2 Diabetes
Mark Yorek, PhD, Principal Investigator
April 2012 - March 2016

Retrospective Retinal Therapy Guided by 3D OCT Image Analysis
Michael Abramoff, Md, PhD, Principal Investigator
May 2010 - April 2016

NORDIC IIHTT Papiledema Evaluation by New Methods of Analyzing OCT
Mona Garvin, PhD, Principal Investigator
February 2012 - January 2016

Objective Methods to Test Visual Dysfunction in the Presence of Cognitive Impairment
Randy Kardon, MD, PhD, Principal Investigator
September 2010 - September 2015

Unfolded Protein Response in Glaucoma Pathogenesis
Markus Kuehn, PhD, Principal Investigator
September 2012 - August 2015

Peroxynitrite, Protein Nitration and Advanced Diabetic Neuropathy
Mark Yorek, PhD, Principal Investigator
February 2013 - March 2015

Longitudinal Idiopathic Intracranial Hypertension Treatment Trial
Michael Wall, MD, Principal Investigator
February 2009 - January 2016

CGRP-induced light aversion in a preclinical migraine model
Andrew Russo, PhD, Principal Investigator
June 2011 - May 2016

Rehabilatation of Diabetic Neuropathy and Retinopathy with P7C3-S243
Mark Yorek, PhD, Principal Investigator
November 2014 - October 2015

Development of Mouse Models for Dissecting LOXL1-Mediated Pathology
Michael Anderson, PhD, Principal Investigator
May 2014 - April 2016

Arnold and Mabel Beckman Initiative for Macular Research
Michael Abramoff, MD, PhD, Principal Investigator
July 2013 - June 2015

A 3 Year, Multi-Center Study to Evaluate Optical Coherence Tomography (OCT) as an Outcome Measure in Patients with Multiple Sclerosis
Randy Kardon, MD, PhD, Principal Investigator
June 2011 - April 2016