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Center for the Prevention and Treatment of Visual Loss

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Dr. Kardon


Randy H. Kardon, MD, Ph.D. 


Randy H. Kardon, MD, Ph.D.

Director, Center for the Prevention and Treatment of Visual Loss

Phone: (319) 338-0581 ext: 7525 or (319) 356-2260



601 HWY 6 West (151)

Iowa City, IA 52246-2208


BS, Pharmacology, University of Iowa

MD, Medicine, University of Iowa

PhD, Pharmacology, University of Iowa

Internship, Medicine, Gundersen Clinic & Lutheran Hospital

Residency, Ophthalmology, University of Iowa

Fellowship, Neuro-Ophthalmology, University of Iowa

Randy Kardon M.D. Ph.D., is tenured Professor of Ophthalmology, served as Director of the Neuro-ophthalmology Service and Neuro-ophthalmology Fellowship Director for over 20 years, and has been faculty at the University of Iowa and Veterans Administration Health Care System for 34 years. He holds the Pomerantz Family Endowed Chair in Ophthalmology and is Director of the Iowa City Veterans Administration Center for the Prevention and Treatment of Visual Loss, competitively funded by the Rehabilitation, Research and Development Division of the Veterans Administration for the last 15 years. The VA Vision Center grant has recently been renewed through June 2029 for $6M in core funding. Dr. Kardon has published over 20 chapters, co-authored a textbook, and has published 265 peer-reviewed journal articles. Dr. Kardon has been fortunate to have had continuous Federal grant funding for 34 years and is presently the Principal Investigator and Co-investigator on 5 major grants externally funded by the Veterans Administration and NIH. Dr. Kardon currently teaches and mentors undergraduate students, medical students, residents and fellows and has received a University of Iowa Collegiate Teaching Award for his teachings and commitment to education. His main areas of current research interest include use of facial features to diagnose and monitor eye and neurological disorders, pupil and eyelid physiology and its clinical application, diagnosis and treatment of light sensitivity and traumatic brain injury, and therapeutic interventions for preserving vision in blinding eye diseases. Dr. Kardon currently investigates structure-function relationships in the visual system using optical coherence tomography (OCT) and deep learning, ocular blood flow using laser speckle flowgraphy, image analysis, and MRI. Dr. Kardon is actively involved in the development of telemedicine tools for objectively evaluating the status of the visual and neurological systems for testing in remote locations and home testing.

Highlighted Publications

1: Gilmore CS, Lim KO, Garvin MK, Wang JK, Ledolter J, Fenske AL, Gentz CL, Nellis J, Armstrong MT, Kardon RH. Association of Optical Coherence Tomography With Longitudinal Neurodegeneration in Veterans With Chronic Mild Traumatic Brain Injury. JAMA Netw Open. 2020 Dec 1;3(12):e2030824. doi:10.1001/jamanetworkopen.2020.30824. PMID: 33351088; PMCID: PMC7756235.

2: Sibony PA, Kupersmith MJ, Kardon RH. Optical Coherence Tomography Neuro-Toolbox for the Diagnosis and Management of Papilledema, Optic Disc Edema, and Pseudopapilledema. J Neuroophthalmol. 2021 Mar 1;41(1):77-92. doi:10.1097/WNO.0000000000001078. PMID: 32909979; PMCID: PMC7882012.

3: Diel RJ, Mehra D, Kardon R, Buse DC, Moulton E, Galor A. Photophobia: shared pathophysiology underlying dry eye disease, migraine and traumatic brain injury leading to central neuroplasticity of the trigeminothalamic pathway. Br J Ophthalmol. 2021 Jun;105(6):751-760. doi: 10.1136/bjophthalmol-2020-316417. Epub 2020 Jul 23. PMID: 32703784; PMCID: PMC8022288.

4: Hussain SF, Raza Z, Cash ATG, Zampieri T, Mazzoli RA, Kardon RH, Gomes RSM. Traumatic brain injury and sight loss in military and veteran populations- a review. Mil Med Res. 2021 Jul 28;8(1):42. doi: 10.1186/s40779-021-00334-3. PMID:34315537; PMCID: PMC8317328.

5: Rea BJ, Davison A, Ketcha MJ, Smith KJ, Fairbanks AM, Wattiez AS, Poolman P, Kardon RH, Russo AF, Sowers LP. Automated detection of squint as a sensitive assay of sex-dependent calcitonin gene-related peptide and amylin-induced pain in mice. Pain. 2022 Aug 1;163(8):1511-1519. doi:10.1097/j.pain.0000000000002537. Epub 2021 Nov 10. PMID: 34772897; PMCID:PMC9085964.

Open Researcher and Contributor ID (ORCID) link: Randy Kardon (0000-0002-3173-7123) - ORCID